Calcium propionate was extensively studied by the FDA before being put into use and was found to be safe. Furthermore, WHO and FAO have not made recommendations on daily intake.
An animal study showed that rats fed 1 to 3 grams of calcium propionate per day continuously for 4 to 5 weeks had no effect on their growth.
Similarly, a 1-year study in rats showed that continuous consumption of 4% calcium propionate at a rate higher than what people normally consume daily had no adverse effects on their health. Most laboratory studies on calcium propionate and their toxicity have been negative, with the exception of a few that have used excessively high doses. For example, in one study, researchers injected large amounts of calcium propionate into the yolk sac of chicken embryos, which resulted in unusual reactions.
On the other hand, it is worth noting that the human body does not store calcium propionate, which means that this compound is not accumulated in the cells. Instead, it is broken down by the gastrointestinal tract and is easily absorbed, metabolized, and eliminated through the waste stream.
An animal study showed that rats fed 1 to 3 grams of calcium propionate per day continuously for 4 to 5 weeks had no effect on their growth.
Similarly, a 1-year study in rats showed that continuous consumption of 4% calcium propionate at a rate higher than what people normally consume daily had no adverse effects on their health. Most laboratory studies on calcium propionate and their toxicity have been negative, with the exception of a few that have used excessively high doses. For example, in one study, researchers injected large amounts of calcium propionate into the yolk sac of chicken embryos, which resulted in unusual reactions.
On the other hand, it is worth noting that the human body does not store calcium propionate, which means that this compound is not accumulated in the cells. Instead, it is broken down by the gastrointestinal tract and is easily absorbed, metabolized, and eliminated through the waste stream.
